The RELAX Study is the first multicenter trial to check out the result of persistent therapy with sildenafil in diastolic heart failure. Sildenafil is a phosphodiesterase-5 (PDE-5) inhibitor, a class of drugs used to take care of erection dysfunction and certain types of pulmonary arterial hypertension. Excellent results with sildenafil in smaller studies and animal models provided the impetus for the analysis. Margaret Redfield, MD, professor of medicine at the Mayo Clinic in Rochester, Minn., and the study’s lead author.
While current treatment for diastolic center failure includes recommendations for weight loss, smoking cessation, and managing blood pressure, there are no medications available for its treatment specifically. Because sildenafil can increase blood supply to the lungs, and in animal studies it improved heart and vascular structure and function, researchers believed the drug would improve heart and lung function for diastolic heart failure patients.
- 6 ounces Fairlife Whole Milk (lactose is removed and has an extra enzyme added)
- I deserve to feel good about myself and my body
- POLL – What’s Your Best Source for Motivation
- No dumping syndrome associated with gastric sleeve
- 3 oz. Greek Yogurt (I used 2% Plain Fage)
- Find trainer
- Blue Cross Pennsylvania Highmark
- Lower success rate
According to Dr. Redfield, although it can be done that factors such as insufficient medication dosage or length of time contributed with their results, she believes this is improbable based on the outcomes of other studies finding advantages from sildenafil. It really is more likely that, in comparison to other …